Steam / Air Mixture Pharmaceutical Autoclaves (FOAF models)
This helps to neutralise the effects of unavoidable excessive pressure within sealed containers when the saturated steam sterilisation is performed, therefore reducing the risk of explosion or permanent deformation). Moist-heat sterilisation is particularly useful for syringes.
The other major advantage of moist heat sterilisation is the cooling by means of a sterile fluid, water or air according to the configuration complying with the cGMP and the FDA
There are two main types of pharmaceutical autoclaves that use counterpressure:
Superheated Water Spray Autoclave (FOW)
The Air-Steam Mixture Autoclave (FOA & FOAF)
FEDEGARI's FOA type pharmaceutical autoclaves have a cylindrical chamber and rectangular doors.
One or several (magnetically coupled) fans located in the upper part of the chamber ensure rapid circulation of the air / steam mixture.
FOA Pharmaceutical Autoclaves are controlled by the Thema 4 system, which allows the user to create programs tailored to the size of the loads to be sterilised, in full conformity with CFR 21 part 11 and cGMP.
The combined action of the fans and the flow deflectors ensure a fast and efficient temperatures homogenization.
After moist-heat sterilization, cooling is achieved both by the injection of sterile air by the fans and the circulation of cold cooling water in the plates located on both sides of the chamber.
The effect is improved by keeping the air pressure high and by maintaining a high level of air circulation.