Manufacturing Stage
Initial rinsing of products
Final rinsing of products
(If the equipment is dried with 70% alcohol after rinsing, it should be diluted in water of the same quality as the water used for the final rinsing)
Potable water
Non sterile Intermediate active pharmaceutical ingredients
Purified water
Sterile
Non sterile pharmaceuticals Sterile non injectables*
*Or of the same level of quality as that used for production if the water quality is superior to « purified water »
WFI water
Sterile injectables*
*The level of quality “highl purified” is accepted if it is justified and validated when depyrogenation follows the final rinsing